| Gene Information | |
|---|---|
| Gene Name | YY1AP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 796 |
| Protein Names | YY1-associated protein 1 (Hepatocellular carcinoma susceptibility protein) (Hepatocellular carcinoma-associated protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000163374 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9H869 |
| Gene Card | YY1AP1 |
| Uniprot ID | Q9H869 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.014780415) |
| Ortholog in Animals | Alpaca_ YY1AP1 ( ortholog_one2one ) Mouse_ Gon4l ( ortholog_one2many ) Rat_ Gon4l ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | GON4L |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart. Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas. {ECO:0000269|PubMed:11710830, ECO:0000269|PubMed:12118372, ECO:0000269|PubMed:14744866}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35098429 rs7539 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11710830, ECO:0000269|PubMed:12118372}. Nucleus {ECO:0000269|PubMed:14744866, ECO:0000269|PubMed:17541814}. Nucleus, nucleoplasm {ECO:0000269|PubMed:27939641}. Nucleus, nucleolus {ECO:0000269|PubMed:27939641}. |
| Mouse PG classification | NA |
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