Gene Information | |
---|---|
Gene Name | CAPN5 |
Organism | Homo sapiens (Human) |
Gene Length | 640 |
Protein Names | Calpain-5 (EC 3.4.22.-) (Calpain htra-3) (New calpain 3) (nCL-3) |
Target Name | NA |
Target Type | NA |
Gene Age | 1488 ( ENSG00000149260 ) |
Evolutionary Stage | Eukaryota |
AlphaFoldDB | O15484 |
Gene Card | CAPN5 |
Uniprot ID | O15484 |
Pfam | PF00168; PF01067; PF00648 |
In ASD | no |
Allosteric Prediction | no (-0.508661559) |
Ortholog in Animals | Alpaca_ CAPN5 ( ortholog_one2one ) Dog_ CAPN5 ( ortholog_one2one ) GuineaPig_ CAPN5 ( ortholog_one2one ) Macaque_ CAPN5 ( ortholog_one2one ) Mouse_ Capn5 ( ortholog_one2one ) Pig_ CAPN5 ( ortholog_one2one ) Rat_ Capn5 ( ortholog_one2one ) Rabbit_ CAPN5 ( ortholog_one2one ) |
Ohnologs | CAPN6 |
Paralogs | CAPN1, PEF1, GCA, SRI, CAPN9, PDCD6, CAPN2, CAPN14, CAPN15, CAPN7, ADGB, CAPN6, CAPN8, CAPN3, CAPN12, CAPNS2, CAPN11, CAPN13, CAPNS1, CAPN10 |
Tissue | NA |
Tissue Specificity | Expressed in many tissues. Strong expression in the photoreceptor cells of the retina, with a punctate pattern of labeling over the nuclei and inner segments with less expression along the other segments and outer plexiform layer. {ECO:0000269|PubMed:23055945}. |
Pharmacological Animal Models | NA |
Gene Ontology (biological process) |
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Gene Ontology (cellular component) |
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Gene Ontology (molecular function) |
|
PDB | 6P3Q (X-ray 2.80A ) |
DBSNP | rs397514601 rs397514602 |
Subcellular location [CC] | NA |
Mouse PG classification | LPG |
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