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Gene Information
Gene Name
YT521
Organism
Homo sapiens (Human)
Gene Length
727
Protein Names
YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B)
Target Name
NA
Target Type
NA
Gene Age
NA
Evolutionary Stage
NA
AlphaFoldDB
Q96MU7
Gene Card
YTHDC1
Uniprot ID
Q96MU7
Pfam
PF04146
In ASD
no
Allosteric Prediction
NA
Ortholog in Animals
NA
Ohnologs
NA
Paralogs
NA
Tissue
NA
Tissue Specificity
NA
Pharmacological Animal Models
NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.031579(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB
2YUD
(NMR
-
)
4R3H
(X-ray
1.90A
)
4R3I
(X-ray
1.80A
)
6RT4
(X-ray
1.49A
)
6RT5
(X-ray
2.30A
)
6RT6
(X-ray
1.46A
)
6RT7
(X-ray
1.73A
)
6SYZ
(X-ray
2.28A
)
6SZ1
(X-ray
1.75A
)
6SZ2
(X-ray
1.52A
)
6SZ3
(X-ray
1.28A
)
6SZL
(X-ray
1.45A
)
6SZN
(X-ray
1.47A
)
6SZR
(X-ray
1.64A
)
6SZT
(X-ray
1.50A
)
6SZX
(X-ray
1.17A
)
6SZY
(X-ray
1.79A
)
6T01
(X-ray
1.50A
)
6T02
(X-ray
1.10A
)
6T03
(X-ray
1.50A
)
6T04
(X-ray
1.50A
)
6T05
(X-ray
1.50A
)
6T06
(X-ray
2.40A
)
6T07
(X-ray
1.50A
)
6T08
(X-ray
1.41A
)
6T09
(X-ray
1.75A
)
6T0A
(X-ray
2.02A
)
6T0C
(X-ray
2.03A
)
6T0D
(X-ray
1.43A
)
6T0O
(X-ray
1.71A
)
6T0X
(X-ray
1.36A
)
6T0Z
(X-ray
1.43A
)
6T10
(X-ray
1.48A
)
6T11
(X-ray
1.49A
)
6T12
(X-ray
1.46A
)
6WE8
(X-ray
1.18A
)
6WE9
(X-ray
1.59A
)
6WEA
(X-ray
1.80A
)
6YKE
(X-ray
1.52A
)
6YKI
(X-ray
1.30A
)
6YKJ
(X-ray
1.60A
)
6YKZ
(X-ray
1.20A
)
6YL0
(X-ray
1.20A
)
6YL8
(X-ray
1.50A
)
6YL9
(X-ray
1.50A
)
6YM2
(X-ray
1.70A
)
6YM6
6YM8
(X-ray
1.50A
)
6YNI
(X-ray
1.36A
)
6YNJ
(X-ray
1.50A
)
6YNK
(X-ray
1.30A
)
6YNL
(X-ray
1.50A
)
6YNM
(X-ray
1.50A
)
6YNN
(X-ray
1.20A
)
6YNO
(X-ray
1.40A
)
6YNP
(X-ray
1.10A
)
6YOQ
(X-ray
1.30A
)
6ZCM
(X-ray
1.24A
)
6ZCN
(X-ray
1.60A
)
6ZD9
(X-ray
1.51A
)
7L4X
(X-ray
1.79A
)
7L4Y
(X-ray
1.79A
)
7P87
(X-ray
1.30A
)
7P88
(X-ray
1.50A
)
7P8A
(X-ray
1.70A
)
7P8B
(X-ray
1.20A
)
7P8F
(X-ray
1.50A
)
7PJ7
(X-ray
1.41A
)
7PJ8
(X-ray
1.40A
)
7PJ9
(X-ray
1.72A
)
7PJA
(X-ray
1.85A
)
7PJB
(X-ray
1.90A
)
7PJP
(X-ray
1.61A
)
7PJQ
(X-ray
1.20A
)
7PO6
(X-ray
1.77A
)
DBSNP
rs3813832
Subcellular location [CC]
Nucleus {ECO:0000269|PubMed:20167602}. Nucleus speckle {ECO:0000269|PubMed:26876937}. Note=Localizes to a novel subnuclear structure, the YT bodies. {ECO:0000250|UniProtKB:Q9QY02}.
Mouse PG classification
NA
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