| Gene Information | |
|---|---|
| Gene Name | PLIN3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 434 |
| Protein Names | Perilipin-3 (47 kDa mannose 6-phosphate receptor-binding protein) (47 kDa MPR-binding protein) (Cargo selection protein TIP47) (Mannose-6-phosphate receptor-binding protein 1) (Placental protein 17) (PP17) |
| Target Name | perilipin-3 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000105355 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O60664 |
| Gene Card | PLIN3 |
| Uniprot ID | O60664 |
| Pfam | PF03036 |
| In ASD | no |
| Allosteric Prediction | no (-1.009330451) |
| Ortholog in Animals | Alpaca_ PLIN3 ( ortholog_one2one ) Dog_ PLIN3 ( ortholog_one2one ) GuineaPig_ PLIN3 ( ortholog_one2one ) Macaque_ PLIN3 ( ortholog_one2one ) Mouse_ Plin3 ( ortholog_one2one ) Pig_ PLIN3 ( ortholog_one2one ) |
| Ohnologs | PLIN2, PLIN1 |
| Paralogs | PLIN5, PLIN4, PLIN2, PLIN1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs8289 rs9973235 |
| Subcellular location [CC] | Lipid droplet {ECO:0000269|PubMed:15545278, ECO:0000269|PubMed:34077757}. Endosome membrane {ECO:0000269|PubMed:15545278}; Peripheral membrane protein {ECO:0000269|PubMed:15545278}; Cytoplasmic side {ECO:0000269|PubMed:15545278}. Cytoplasm {ECO:0000269|PubMed:15545278, ECO:0000269|PubMed:26357594, ECO:0000269|PubMed:9590177}. Note=Membrane associated on endosomes (PubMed:15545278). Detected in the envelope and the core of lipid bodies and in lipid sails (PubMed:15545278). {ECO:0000269|PubMed:15545278}. |
| Mouse PG classification | NA |
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