Gene Information
Gene NameYRDC
OrganismHomo sapiens (Human)
Gene Length279
Protein NamesThreonylcarbamoyl-AMP synthase (EC 2.7.7.87) (Dopamine receptor-interacting protein 3) (Ischemia/reperfusion-inducible protein homolog) (hIRIP)
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000196449 )
Evolutionary StageCellular_organisms
AlphaFoldDBQ86U90
Gene CardYRDC
Uniprot IDQ86U90
PfamPF01300
In ASDno
Allosteric Predictionno (-1.233868527)
Ortholog in AnimalsAlpaca_ YRDC ( ortholog_one2one )
Dog_ YRDC ( ortholog_one2one )
GuineaPig_ YRDC ( ortholog_one2one )
Macaque_ YRDC ( ortholog_one2one )
Mouse_ Yrdc ( ortholog_one2one )
Pig_ YRDC ( ortholog_one2one )
Rat_ Yrdc ( ortholog_one2one )
Rabbit_ YRDC ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityUbiquitously expressed. {ECO:0000269|PubMed:12730717}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.066667(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:29760464}. Mitochondrion {ECO:0000269|PubMed:29760464}. Cell membrane {ECO:0000250|UniProtKB:Q3U5F4};
Peripheral membrane protein {ECO:0000250|UniProtKB:Q3U5F4}. Note=A large fraction localizes in the cytoplasm, whereas a smaller fraction is imported to mitochondria. {ECO:0000269|PubMed:29760464}.
Mouse PG classificationNA
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