Gene Information
Gene NameYME1L
OrganismHomo sapiens (Human)
Gene Length773
Protein NamesATP-dependent zinc metalloprotease YME1L1 (EC 3.4.24.-) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin-associated metalloprotease) (PAMP) (YME1-like protein 1)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ96TA2
Gene CardYME1L1
Uniprot IDQ96TA2
PfamPF00004; PF17862; PF01434
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityHigh expression in cardiac and skeletal muscle mitochondria. {ECO:0000269|PubMed:22262461}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.002657(Rat);0.057143(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs1057519312 
Subcellular location [CC]Mitochondrion inner membrane {ECO:0000269|PubMed:10843804, ECO:0000269|PubMed:22262461}. Mitochondrion {ECO:0000269|PubMed:26923599, ECO:0000269|PubMed:27495975}.
Mouse PG classificationNA
click here to return to the previous page