| Gene Information | |
|---|---|
| Gene Name | NDUFC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 119 |
| Protein Names | NADH dehydrogenase [ubiquinone] 1 subunit C2 (Complex I-B14.5b) (CI-B14.5b) (Human lung cancer oncogene 1 protein) (HLC-1) (NADH-ubiquinone oxidoreductase subunit B14.5b) |
| Target Name | nadh dehydrogenase [ubiquinone] 1 subunit c2 |
| Target Type | NA |
| Gene Age | 8 ( ENSG00000151366 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O95298 |
| Gene Card | NDUFC2 |
| Uniprot ID | O95298 |
| Pfam | PF06374 |
| In ASD | no |
| Allosteric Prediction | no (-0.867205042) |
| Ortholog in Animals | Alpaca_ NDUFC2 ( ortholog_one2one ) Dog_ NDUFC2 ( ortholog_one2one ) GuineaPig_ NDUFC2 ( ortholog_one2one ) Macaque_ NDUFC2 ( ortholog_one2one ) Mouse_ Ndufc2 ( ortholog_one2one ) Pig_ NDUFC2 ( ortholog_one2one ) Rat_ Ndufc2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.642868(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5XTC (EM 3.70A ) 5XTD (EM 3.70A ) 5XTH (EM 3.90A ) 5XTI (EM 17.40A ) |
| DBSNP | rs8875 rs1306743145 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000305|PubMed:12611891}; Single-pass membrane protein {ECO:0000255}; Matrix side {ECO:0000305}. |
| Mouse PG classification | NA |
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