| Gene Information | |
|---|---|
| Gene Name | RAP2A |
| Organism | Homo sapiens (Human) |
| Gene Length | 183 |
| Protein Names | Ras-related protein Rap-2a (EC 3.6.5.2) (RbBP-30) |
| Target Name | ras-related protein rap-2a |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000125249 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P10114 |
| Gene Card | RAP2A |
| Uniprot ID | P10114 |
| Pfam | PF00071 |
| In ASD | no |
| Allosteric Prediction | yes (0.166364969) |
| Ortholog in Animals | Alpaca_ RAP2A ( ortholog_one2one ) Dog_ RAP2A ( ortholog_one2one ) Macaque_ RAP2A ( ortholog_one2one ) Mouse_ Rap2a ( ortholog_one2one ) Pig_ RAP2A ( ortholog_one2one ) Rat_ Rap2a ( ortholog_one2one ) |
| Ohnologs | RAP2C, RAP2B |
| Paralogs | RRAS, RHEB, KRAS, DIRAS1, RRAS2, RAP2B, HRAS, RERG, RASL12, RRAD, RIT1, DIRAS2, ERAS, NKIRAS1, RALB, RASD2, GEM, DIRAS3, MRAS, RASD1, REM1, NKIRAS2, RALA, RAP1A, RASL11B, RAP1B, RASL10A, RASL11A, REM2, RERGL, RIT2, RHEBL1, NRAS, RAP2C, RASL10B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1KAO (X-ray 1.70A ) 2RAP (X-ray 2.60A ) 3RAP (X-ray 2.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Midbody. Note=May also localize to the Golgi (PubMed:7962206) and the gelatinase-containing granules of neutrophils (PubMed:8391995). Colocalizes with RASGEF1B to midbody at telophase (PubMed:23894443). {ECO:0000269|PubMed:23894443, ECO:0000269|PubMed:7962206, ECO:0000269|PubMed:8391995}. |
| Mouse PG classification | NA |
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