| Gene Information | |
|---|---|
| Gene Name | YEATS3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 568 |
| Protein Names | Protein AF-9 (ALL1-fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P42568 |
| Gene Card | MLLT3 |
| Uniprot ID | P42568 |
| Pfam | PF17793; PF03366 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Enriched in undifferentiated hematopoietic stem cells in fetal liver, cord blood and bone marrow. {ECO:0000269|PubMed:31776511}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.013775(Mouse);NULL(Rat);0.029032(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2LM0 (NMR - ) 2MV7 (NMR - ) 2N4Q (NMR - ) 2NDF (NMR - ) 2NDG (NMR - ) 4TMP (X-ray 2.30A ) 5HJB (X-ray 2.70A ) 5HJD (X-ray 2.81A ) 5YYF (X-ray 1.90A ) 6B7G (NMR - ) 6L5Z (X-ray 3.05A ) 6LS6 (X-ray 2.20A ) 6MIL (X-ray 1.93A ) 6MIM (X-ray 2.52A ) 7EIC (X-ray 1.95A ) 7EID (X-ray 2.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00376, ECO:0000269|PubMed:27105114}. Chromosome {ECO:0000269|PubMed:25417107, ECO:0000269|PubMed:27105114}. Note=Colocalizes with acylated histone H3 (PubMed:25417107, PubMed:27105114). Colocalizes with histone H3 crotonylated at 'Lys-18' (H3K18cr) (PubMed:27105114). {ECO:0000269|PubMed:25417107, ECO:0000269|PubMed:27105114}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |