Gene Information
Gene NameCDC16
OrganismHomo sapiens (Human)
Gene Length620
Protein NamesCell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6)
Target NameNA
Target TypeNA
Gene Age1714 ( ENSG00000130177 )
Evolutionary StageCellular_organisms
AlphaFoldDBQ13042
Gene CardCDC16
Uniprot IDQ13042
PfamNA
In ASDno
Allosteric Predictionno (-0.459701818)
Ortholog in AnimalsAlpaca_ CDC16 ( ortholog_one2one )
Dog_ CDC16 ( ortholog_one2one )
GuineaPig_ CDC16 ( ortholog_one2one )
Macaque_ CDC16 ( ortholog_one2one )
Mouse_ Cdc16 ( ortholog_one2one )
Pig_ CDC16 ( ortholog_one2one )
Rat_ Cdc16 ( ortholog_one2one )
Rabbit_ CDC16 ( ortholog_one2one )
OhnologsNA
ParalogsANAPC7, CDC27, CDC23
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);0.257913(Mouse);NULL(Rat);0.160679(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3HYM  (X-ray  2.80A  4UI9  (EM  3.60A  5A31  (EM  4.30A  5G04  (EM  4.00A  5G05  (EM  3.40A  5KHR  (EM  6.10A  5KHU  (EM  4.80A  5L9T  (EM  6.40A  5L9U  (EM  6.40A  5LCW  (EM  4.00A  6Q6G  (EM  3.20A  6Q6H  (EM  3.20A  6TLJ  (EM  3.80A  6TM5  (EM  3.90A  6TNT  (EM  3.78A  7QE7  (EM  2.90A 
DBSNP NA 
Subcellular location [CC]Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:7736578}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:7736578}. Note=Colocalizes with CDC27 to the centrosome at all stages of the cell cycle and to the mitotic spindle.
Mouse PG classificationNA
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