| Gene Information | |
|---|---|
| Gene Name | XYLT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 865 |
| Protein Names | Xylosyltransferase 2 (EC 2.4.2.26) (Peptide O-xylosyltransferase 1) (Xylosyltransferase II) (XT-II) (XylT-II) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000015532 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H1B5 |
| Gene Card | XYLT2 |
| Uniprot ID | Q9H1B5 |
| Pfam | PF02485; PF12529 |
| In ASD | no |
| Allosteric Prediction | no (-1.162193019) |
| Ortholog in Animals | Alpaca_ XYLT2 ( ortholog_one2one ) Dog_ XYLT2 ( ortholog_one2one ) GuineaPig_ XYLT2 ( ortholog_one2one ) Mouse_ Xylt2 ( ortholog_one2one ) Pig_ XYLT2 ( ortholog_one2one ) Rat_ Xylt2 ( ortholog_one2one ) Rabbit_ XYLT2 ( ortholog_one2one ) |
| Ohnologs | XYLT1 |
| Paralogs | WSCD1, GCNT2, GCNT7, XYLT1, GCNT3, GCNT1, GCNT4, WSCD2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed at higher level in kidney and pancreas. {ECO:0000269|PubMed:11099377}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs113835371 rs739990 rs748114111 rs12451299 rs72832454 rs6504649 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. Secreted {ECO:0000269|PubMed:17189265, ECO:0000269|PubMed:25748573}. |
| Mouse PG classification | LPG |
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