| Gene Information | |
|---|---|
| Gene Name | XT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 959 |
| Protein Names | Xylosyltransferase 1 (EC 2.4.2.26) (Peptide O-xylosyltransferase 1) (Xylosyltransferase I) (XT-I) (XylT-I) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q86Y38 |
| Gene Card | XYLT1 |
| Uniprot ID | Q86Y38 |
| Pfam | PF02485; PF12529 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed at higher level in placenta, kidney and pancreas. Weakly expressed in skeletal muscle. {ECO:0000269|PubMed:11099377}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.088150(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6EJ7 (X-ray 2.00A ) 6EJ8 (X-ray 2.09A ) 6EJ9 (X-ray 2.02A ) 6EJA (X-ray 1.94A ) 6EJB (X-ray 2.56A ) 6EJC (X-ray 2.06A ) 6EJD (X-ray 2.68A ) 6EJE (X-ray 2.43A ) 6FOA (X-ray 1.87A ) |
| DBSNP | rs61758388 rs28709752 rs201009902 rs587777366 rs587777367 rs79030430 rs12325439 rs7200466 rs35309694 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000269|PubMed:23982343, ECO:0000269|PubMed:28462984}; Single-pass type II membrane protein {ECO:0000305}. Secreted {ECO:0000269|PubMed:11087729, ECO:0000269|PubMed:16571645}. Note=Detected predominantly in the Golgi apparatus. {ECO:0000269|PubMed:28462984}. |
| Mouse PG classification | NA |
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