| Gene Information | |
|---|---|
| Gene Name | XPCC |
| Organism | Homo sapiens (Human) |
| Gene Length | 940 |
| Protein Names | DNA repair protein complementing XP-C cells (Xeroderma pigmentosum group C-complementing protein) (p125) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q01831 |
| Gene Card | XPC |
| Uniprot ID | Q01831 |
| Pfam | PF10403; PF10404; PF10405; PF03835 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001704(Rat);0.0125(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2A4J (NMR - ) 2GGM (X-ray 2.35A ) 2OBH (X-ray 1.80A ) 2RVB (NMR - ) |
| DBSNP | rs1870134 rs2229089 rs3731063 rs35629274 rs3731126 rs74737358 rs2227999 rs2228000 rs6413541 rs3731130 rs3731130 rs3731139 rs3731140 rs3731152 rs3731177 rs2228001 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11279143, ECO:0000269|PubMed:18682493, ECO:0000269|PubMed:8692695}. Chromosome {ECO:0000269|PubMed:29973595}. Cytoplasm {ECO:0000269|PubMed:18682493}. Note=Omnipresent in the nucleus and consistently associates with and dissociates from DNA in the absence of DNA damage (PubMed:18682493). Continuously shuttles between the cytoplasm and the nucleus, which is impeded by the presence of NER lesions (PubMed:18682493). {ECO:0000269|PubMed:18682493}. |
| Mouse PG classification | NA |
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