| Gene Information | |
|---|---|
| Gene Name | XPB |
| Organism | Homo sapiens (Human) |
| Gene Length | 782 |
| Protein Names | General transcription and DNA repair factor IIH helicase subunit XPB (TFIIH subunit XPB) (EC 3.6.4.12) (Basic transcription factor 2 89 kDa subunit) (BTF2 p89) (DNA excision repair protein ERCC-3) (DNA repair protein complementing XP-B cells) (TFIIH basal transcription factor complex 89 kDa subunit) (TFIIH 89 kDa subunit) (TFIIH p89) (Xeroderma pigmentosum group B-complementing protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P19447 |
| Gene Card | ERCC3 |
| Uniprot ID | P19447 |
| Pfam | PF16203; PF13625; PF04851 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.599373(Rat);0.269824(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4ERN (X-ray 1.80A ) 5IVW (EM 10.00A ) 5IY6 (EM 7.20A ) 5IY7 (EM 8.60A ) 5IY8 (EM 7.90A ) 5IY9 (EM 6.30A ) 5OF4 (EM 4.40A ) 6NMI (EM 3.70A ) 6O9L (EM 7.20A ) 6O9M (EM 4.40A ) 6RO4 (EM 3.50A ) 7AD8 (EM 3.50A ) 7EGB (EM 3.30A ) 7EGC (EM 3.90A ) 7ENA (EM 4.07A ) 7ENC (EM 4.13A ) 7LBM (EM 4.80A ) 7NVR (EM 4.50A ) 7NVV (EM 2.90A ) 7NVW (EM 4.30A ) 7NVX (EM 3.90A ) 7NVY (EM 7.30A ) 7NVZ (EM 7.20A ) 7NW0 (EM 6.60A ) |
| DBSNP | rs121913045 rs1805161 rs121913046 rs1805162 rs4150521 rs4150522 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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