| Gene Information | |
|---|---|
| Gene Name | XK |
| Organism | Homo sapiens (Human) |
| Gene Length | 444 |
| Protein Names | Endoplasmic reticulum membrane adapter protein XK (Kell complex 37 kDa component) (Kx antigen) (Membrane transport protein XK) (XK-related protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000047597 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P51811 |
| Gene Card | XK |
| Uniprot ID | P51811 |
| Pfam | PF09815 |
| In ASD | no |
| Allosteric Prediction | no (-0.133944683) |
| Ortholog in Animals | Alpaca_ XK ( ortholog_one2one ) Dog_ XK ( ortholog_one2one ) GuineaPig_ XK ( ortholog_one2one ) Macaque_ XK ( ortholog_one2one ) Mouse_ Xk ( ortholog_one2one ) Pig_ XK ( ortholog_one2one ) Rat_ Xk ( ortholog_one2one ) Rabbit_ XK ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | XKRX, XKR3 |
| Tissue | small.intestine |
| Tissue Specificity | High levels in skeletal muscle, heart, brain, and pancreas; low levels in placenta, lung, liver, and kidney. {ECO:0000269|PubMed:8004674}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs28933690 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:32845802, ECO:0000269|PubMed:9593744}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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