| Gene Information | |
|---|---|
| Gene Name | XIP |
| Organism | Homo sapiens (Human) |
| Gene Length | 91 |
| Protein Names | Ragulator complex protein LAMTOR5 (Hepatitis B virus X-interacting protein) (HBV X-interacting protein) (HBX-interacting protein) (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O43504 |
| Gene Card | LAMTOR5 |
| Uniprot ID | O43504 |
| Pfam | PF16672 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in skeletal and cardiac muscle, followed by pancreas, kidney, liver, brain, placenta and lung. Elevated levels in both cancerous and non-cancerous liver tissue of patients with chronic HBV infection compared with hepatic tissue without HBV infection. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3MS6 (X-ray 2.08A ) 3MSH (X-ray 1.51A ) 5VOK (X-ray 2.89A ) 5X6U (X-ray 2.40A ) 5X6V (X-ray 2.02A ) 5Y38 (X-ray 2.80A ) 5Y39 (X-ray 2.65A ) 5Y3A (X-ray 2.90A ) 5YK3 (X-ray 3.01A ) 6B9X (X-ray 1.42A ) 6EHP (X-ray 2.30A ) 6EHR (X-ray 2.90A ) 6NZD (EM 3.60A ) 6U62 (EM 3.18A ) 6ULG (EM 3.31A ) 6WJ2 (EM 3.20A ) 6WJ3 (EM 3.90A ) 7T3A (EM 4.00A ) 7T3B (EM 3.90A ) 7T3C (EM 4.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Lysosome {ECO:0000269|PubMed:22980980}. Cytoplasm, cytosol {ECO:0000269|PubMed:12773388}. |
| Mouse PG classification | NA |
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