Gene Information
Gene NameXE169
OrganismHomo sapiens (Human)
Gene Length1560
Protein NamesLysine-specific demethylase 5C (EC 1.14.11.67) (Histone demethylase JARID1C) (Jumonji/ARID domain-containing protein 1C) (Protein SmcX) (Protein Xe169) ([histone H3]-trimethyl-L-lysine(4) demethylase 5C)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBP41229
Gene CardKDM5C
Uniprot IDP41229
PfamPF01388; PF02373; PF02375; PF00628; PF08429; PF02928
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in all tissues examined. Highest levels found in brain and skeletal muscle. {ECO:0000269|PubMed:15586325}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.013333(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2JRZ  (NMR  5FWJ  (X-ray  2.10A 
DBSNP rs199422235  rs199422237  rs1057518697  rs1057517955  rs199422234 
Subcellular location [CC]Nucleus {ECO:0000255|PROSITE-ProRule:PRU00355, ECO:0000255|PROSITE-ProRule:PRU00537, ECO:0000269|PubMed:17468742}.
Mouse PG classificationNA
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