| Gene Information | |
|---|---|
| Gene Name | CISD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 108 |
| Protein Names | CDGSH iron-sulfur domain-containing protein 1 (MitoNEET) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000122873 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NZ45 |
| Gene Card | CISD1 |
| Uniprot ID | Q9NZ45 |
| Pfam | PF10660; PF09360 |
| In ASD | no |
| Allosteric Prediction | no (-1.070596454) |
| Ortholog in Animals | Alpaca_ CISD1 ( ortholog_one2one ) Mouse_ Cisd1 ( ortholog_one2one ) Rat_ Cisd1 ( ortholog_one2one ) Rabbit_ CISD1 ( ortholog_one2one ) |
| Ohnologs | CISD2 |
| Paralogs | CISD3, CISD2 |
| Tissue | NA |
| Tissue Specificity | Expression is reduced in cells derived from cystic fibrosis patients. {ECO:0000269|PubMed:18047834}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2QD0 (X-ray 1.81A ) 2QH7 (X-ray 1.50A ) 2R13 (X-ray 1.80A ) 3EW0 (X-ray 1.40A ) 3LPQ (X-ray 1.70A ) 3REE (X-ray 1.76A ) 4EZF (X-ray 1.19A ) 4F1E (X-ray 2.40A ) 4F28 (X-ray 1.55A ) 4F2C (X-ray 1.35A ) 6DE9 (X-ray 1.95A ) 7P0O (X-ray 1.65A ) |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion outer membrane {ECO:0000269|PubMed:17376863, ECO:0000269|PubMed:17766439, ECO:0000269|PubMed:17905743, ECO:0000269|PubMed:18047834}; Single-pass type III membrane protein {ECO:0000269|PubMed:17376863, ECO:0000269|PubMed:17766439, ECO:0000269|PubMed:17905743, ECO:0000269|PubMed:18047834}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |