| Gene Information | |
|---|---|
| Gene Name | XAB2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 855 |
| Protein Names | Pre-mRNA-splicing factor SYF1 (Protein HCNP) (XPA-binding protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000076924 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9HCS7 |
| Gene Card | XAB2 |
| Uniprot ID | Q9HCS7 |
| Pfam | PF13181 |
| In ASD | no |
| Allosteric Prediction | no (-0.685620732) |
| Ortholog in Animals | Alpaca_ XAB2 ( ortholog_one2one ) Dog_ XAB2 ( ortholog_one2one ) GuineaPig_ XAB2 ( ortholog_one2one ) Macaque_ XAB2 ( ortholog_one2one ) Mouse_ Xab2 ( ortholog_one2one ) Pig_ XAB2 ( ortholog_one2one ) Rat_ Xab2 ( ortholog_one2one ) Rabbit_ XAB2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CRNKL1, PRPF6 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.197742(Rat);0.151859(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5MQF (EM 5.90A ) 5XJC (EM 3.60A ) 5YZG (EM 4.10A ) 5Z56 (EM 5.10A ) 5Z57 (EM 6.50A ) 6FF7 (EM 4.50A ) 6ICZ (EM 3.00A ) 6ID0 (EM 2.90A ) 6ID1 (EM 2.86A ) 6QDV (EM 3.30A ) 7A5P (EM 5.00A ) 7ABI (EM 8.00A ) 7W59 (EM 3.60A ) 7W5A (EM 3.60A ) 7W5B (EM 4.30A ) |
| DBSNP | rs4134822 rs4134850 rs4134865 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11991638, ECO:0000269|PubMed:25599396, ECO:0000269|PubMed:28076346, ECO:0000269|PubMed:28502770}. Note=Detected in the splicing complex carrying pre-mRNA. {ECO:0000250|UniProtKB:Q99PK0}. |
| Mouse PG classification | NA |
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