| Gene Information | |
|---|---|
| Gene Name | X11 |
| Organism | Homo sapiens (Human) |
| Gene Length | 837 |
| Protein Names | Amyloid-beta A4 precursor protein-binding family A member 1 (Adapter protein X11alpha) (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q02410 |
| Gene Card | APBA1 |
| Uniprot ID | Q02410 |
| Pfam | PF00595; PF00640 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Brain and spinal cord. Isoform 2 is expressed in testis and brain, but not detected in lung, liver or spleen. {ECO:0000269|PubMed:23737971}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.078589(Rat);0.018182(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1AQC (X-ray 2.30A ) 1U37 (NMR - ) 1U38 (NMR - ) 1U39 (NMR - ) 1U3B (NMR - ) 1X11 (X-ray 2.50A ) 1X45 (NMR - ) 1Y7N (NMR - ) |
| DBSNP | rs34788368 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:20531236}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:20531236}. Nucleus {ECO:0000269|PubMed:20531236}. Note=Only about 5% of the protein is located in the nucleus.; [Isoform 2]: Golgi apparatus {ECO:0000269|PubMed:23737971}. |
| Mouse PG classification | NA |
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