| Gene Information | |
|---|---|
| Gene Name | PI12 |
| Organism | Homo sapiens (Human) |
| Gene Length | 410 |
| Protein Names | Neuroserpin (Peptidase inhibitor 12) (PI-12) (Serpin I1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q99574 |
| Gene Card | SERPINI1 |
| Uniprot ID | Q99574 |
| Pfam | PF00079 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in brain cortex and hippocampus pyramidal neurons (at protein level) (PubMed:17040209). Predominantly expressed in the brain (PubMed:9070919). {ECO:0000269|PubMed:17040209, ECO:0000269|PubMed:9070919}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3F02 (X-ray 1.80A ) 3F5N (X-ray 3.15A ) 3FGQ (X-ray 2.09A ) |
| DBSNP | rs121909051 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:17040209}. Cytoplasmic vesicle, secretory vesicle lumen {ECO:0000305|PubMed:17040209}. Perikaryon {ECO:0000269|PubMed:17040209}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |