| Gene Information | |
|---|---|
| Gene Name | MMP28 |
| Organism | Homo sapiens (Human) |
| Gene Length | 520 |
| Protein Names | Matrix metalloproteinase-28 (MMP-28) (EC 3.4.24.-) (Epilysin) |
| Target Name | matrix metalloproteinase-28 |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000271447 ) 3 ( ENSG00000278843 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9H239 |
| Gene Card | MMP28 |
| Uniprot ID | Q9H239 |
| Pfam | PF00045; PF00413; PF01471 |
| In ASD | no |
| Allosteric Prediction | no (-1.278200253) |
| Ortholog in Animals | Alpaca_ MMP28 ( ortholog_one2one ) Dog_ MMP28 ( ortholog_one2one ) GuineaPig_ MMP28 ( ortholog_one2one ) Macaque_ MMP28 ( ortholog_one2one ) Mouse_ Mmp28 ( ortholog_one2one ) Pig_ MMP28 ( ortholog_one2one ) Rat_ Mmp28 ( ortholog_one2one ) Rabbit_ MMP28 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MMP24, MMP16, MMP21, MMP14, MMP2, MMP1, MMP19, MMP23B, MMP10, MMP9, MMP12, MMP15, MMP27, MMP17, MMP25, MMP13, MMP7, MMP20, MMP26, HPX, MMP8, MMP3, MMP11 |
| Tissue | NA |
| Tissue Specificity | Expressed at high levels in testes and lung. Low levels are detected in kidney, pancreas and skin. Also expressed in fetal lung, brain, skeletal muscle and kidney. Expressed selectively in keratinocytes. Widely expressed in several carcinomas as well. Is up-regulated in response to injury in the skin. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix. |
| Mouse PG classification | NA |
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