| Gene Information | |
|---|---|
| Gene Name | WRCH2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 236 |
| Protein Names | Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96L33 |
| Gene Card | RHOV |
| Uniprot ID | Q96L33 |
| Pfam | PF00071 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in pancreas, placenta, and fetal brain. {ECO:0000269|PubMed:11956592}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q9Z1Y0}; Lipid-anchor {ECO:0000250|UniProtKB:Q9Z1Y0}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9Z1Y0}. Endosome membrane {ECO:0000250|UniProtKB:Q9Z1Y0}; Lipid-anchor {ECO:0000250|UniProtKB:Q9Z1Y0}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9Z1Y0}. Note=Treatment with TNF activates endosomal but not plasma membrane RHOV. {ECO:0000250|UniProtKB:Q9Z1Y0}. |
| Mouse PG classification | NA |
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