| Gene Information | |
|---|---|
| Gene Name | TRIM55 |
| Organism | Homo sapiens (Human) |
| Gene Length | 548 |
| Protein Names | Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF-2) (MuRF2) (RING finger protein 29) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000147573 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9BYV6 |
| Gene Card | TRIM55 |
| Uniprot ID | Q9BYV6 |
| Pfam | PF00643; PF13445 |
| In ASD | no |
| Allosteric Prediction | no (-0.606952074) |
| Ortholog in Animals | Alpaca_ TRIM55 ( ortholog_one2one ) Dog_ TRIM55 ( ortholog_one2one ) GuineaPig_ TRIM55 ( ortholog_one2one ) Macaque_ TRIM55 ( ortholog_one2one ) Mouse_ Trim55 ( ortholog_one2one ) Pig_ TRIM55 ( ortholog_one2one ) Rat_ Trim55 ( ortholog_one2one ) Rabbit_ TRIM55 ( ortholog_one2one ) |
| Ohnologs | MID1, TRIM36, TRIM63, TRIM46 |
| Paralogs | TRIM42, TRIM13, TRIM31, TRIM49B, TRIM49C, TRIM49, TRIM33, TRIM69, TRIM71, TRIM77, TRIM28, TRIM3, TRIM46, TRIM58, TRIM38, TRIM5, TRIM37, MID1, TRIM7, TRIM36, TRIM44, TRIML2, TRIM2, TRIM63, TRIM73, TRIM74, TRIM65, TRIML1, MID2, TRIM32, TRIM14, TRIM34, TRIM52, TRIM41, TRIM11, PML, TRIM43, TRIM43B, TRIM21, TRIM6, TRIM27, TRIM40, TRIM51G, TRIM51, TRIM9, TRIM67, TRIM25, TRIM49D1, TRIM48, TRIM49D2, TRIM68, TRIM17, TRIM24, TRIM64C, TRIM64, TRIM64B, TRIM60, TRIM61, TRIM4, TRIM10, BSPRY, TRIM56, TRIM29, TRIM8, MEFV, TRIM15, TRIM22, TRIM35, TRIM16, TRIM47, TRIM45, TRIM72, TRIM62, TRIM50, TRIM75, TRIM66, RNF39, TRIM26, TRIM39, TRIM54 |
| Tissue | heart, liver, testis, atrium |
| Tissue Specificity | Highly expressed in muscle. Low-level expression in liver. {ECO:0000269|PubMed:11243782}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1320007526 rs769797275 rs61741078 rs1279027783 rs770907206 rs7843605 rs200545859 rs755876598 rs770146015 rs781152511 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Nuclear under atrophic conditions and upon mechanical signals. Localizes to the sarcomeric M-band in cardiomyocytes. Colocalizes in part with microtubules (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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