| Gene Information | |
|---|---|
| Gene Name | WNT3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 355 |
| Protein Names | Proto-oncogene Wnt-3 (Proto-oncogene Int-4 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000108379 ) 3 ( ENSG00000277626 ) 3 ( ENSG00000277641 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P56703 |
| Gene Card | WNT3 |
| Uniprot ID | P56703 |
| Pfam | PF00110 |
| In ASD | no |
| Allosteric Prediction | no (-0.450566901) |
| Ortholog in Animals | Alpaca_ WNT3 ( ortholog_one2one ) Dog_ WNT3 ( ortholog_one2one ) GuineaPig_ WNT3 ( ortholog_one2one ) Macaque_ WNT3 ( ortholog_one2one ) Mouse_ Wnt3 ( ortholog_one2one ) Pig_ WNT3 ( ortholog_one2one ) Rat_ Wnt3 ( ortholog_one2one ) Rabbit_ WNT3 ( ortholog_one2one ) |
| Ohnologs | WNT7B, WNT1, WNT3A, WNT7A |
| Paralogs | WNT5A, WNT6, WNT4, WNT2B, WNT2, WNT9B, WNT16, WNT8B, WNT11, WNT3A, WNT7B, WNT5B, WNT10A, WNT9A, WNT7A, WNT10B, WNT1, WNT8A |
| Tissue | skin, zone.of.skin, lower.leg.skin, suprapubic.skin |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6AHY (X-ray 2.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000305}. Secreted {ECO:0000269|PubMed:26902720}. |
| Mouse PG classification | LPG |
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