Gene Information
Gene NameTSPAN4
OrganismHomo sapiens (Human)
Gene Length238
Protein NamesTetraspanin-4 (Tspan-4) (Novel antigen 2) (NAG-2) (Transmembrane 4 superfamily member 7)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000214063 )
Evolutionary StageEumetazoa
AlphaFoldDBO14817
Gene CardTSPAN4
Uniprot IDO14817
PfamPF00335
In ASDno
Allosteric Predictionno (-0.511409868)
Ortholog in AnimalsAlpaca_ TSPAN4 ( ortholog_one2one )
Dog_ TSPAN4 ( ortholog_one2one )
GuineaPig_ TSPAN4 ( ortholog_one2one )
Macaque_ TSPAN4 ( ortholog_one2one )
Mouse_ Tspan4 ( ortholog_one2one )
Pig_ TSPAN4 ( ortholog_one2one )
Rat_ Tspan4 ( ortholog_one2one )
OhnologsTSPAN9, TSPAN11, CD53
ParalogsROM1, TSPAN12, CD63, TSPAN10, CD9, TSPAN6, TSPAN5, CD37, CD151, TSPAN1, TSPAN31, UPK1A, TSPAN17, TSPAN11, TSPAN32, TSPAN8, TSPAN13, TSPAN2, CD53, TSPAN9, TSPAN18, CD81, CD82, TSPAN16, TSPAN19, TSPAN7, UPK1B, TSPAN3, TSPAN14, TSPAN15, PRPH2, TSPAN33
TissueNA
Tissue SpecificityExpressed in multiple tissues but is absent in brain, lymphoid cells, and platelets.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Membrane;
Multi-pass membrane protein.
Mouse PG classificationNA
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