| Gene Information | |
|---|---|
| Gene Name | C6orf68 |
| Organism | Homo sapiens (Human) |
| Gene Length | 293 |
| Protein Names | Dehydrodolichyl diphosphate synthase complex subunit NUS1 (EC 2.5.1.87) (Cis-prenyltransferase subunit NgBR) (Nogo-B receptor) (NgBR) (Nuclear undecaprenyl pyrophosphate synthase 1 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96E22 |
| Gene Card | NUS1 |
| Uniprot ID | Q96E22 |
| Pfam | PF01255 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.010990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6W2L (X-ray 2.31A ) 6Z1N (X-ray 2.30A ) 7PAX (X-ray 2.00A ) 7PAY (X-ray 2.40A ) 7PB0 (X-ray 2.30A ) 7PB1 (X-ray 2.59A ) |
| DBSNP | rs28362518 rs28362519 rs1052237 rs1052239 rs1132147 rs886037858 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:19723497, ECO:0000269|PubMed:21572394}; Multi-pass membrane protein {ECO:0000303|PubMed:21572394}. Note=Colocalizes with Nogo-B during VEGF and wound healing angiogenesis. {ECO:0000269|PubMed:19723497}. |
| Mouse PG classification | NA |
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