| Gene Information | |
|---|---|
| Gene Name | WIPF2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 440 |
| Protein Names | WAS/WASL-interacting protein family member 2 (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein) (WIP-related protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000171475 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8TF74 |
| Gene Card | WIPF2 |
| Uniprot ID | Q8TF74 |
| Pfam | PF02205 |
| In ASD | no |
| Allosteric Prediction | no (-0.704143012) |
| Ortholog in Animals | Alpaca_ WIPF2 ( ortholog_one2one ) Dog_ WIPF2 ( ortholog_one2one ) GuineaPig_ WIPF2 ( ortholog_one2one ) Macaque_ WIPF2 ( ortholog_one2one ) Mouse_ Wipf2 ( ortholog_one2one ) Pig_ WIPF2 ( ortholog_one2one ) Rat_ Wipf2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | WIPF3, WIPF1 |
| Tissue | NA |
| Tissue Specificity | Expressed mainly in brain, colon, lung and stomach (at protein level). Ubiquitously expressed, with high expression in brain, kidney, lung, and placenta. {ECO:0000269|PubMed:11829459, ECO:0000269|PubMed:12213210}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.029817(Mouse);NULL(Rat);0.044444(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11829459, ECO:0000269|PubMed:12213210}. Note=Localized to stress fibers and bundles of actin filaments. |
| Mouse PG classification | NA |
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