| Gene Information | |
|---|---|
| Gene Name | WHSC1L1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1437 |
| Protein Names | Histone-lysine N-methyltransferase NSD3 (EC 2.1.1.370) (EC 2.1.1.371) (Nuclear SET domain-containing protein 3) (Protein whistle) (WHSC1-like 1 isoform 9 with methyltransferase activity to lysine) (Wolf-Hirschhorn syndrome candidate 1-like protein 1) (WHSC1-like protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9BZ95 |
| Gene Card | NSD3 |
| Uniprot ID | Q9BZ95 |
| Pfam | PF17907; PF17982; PF00855; PF00856 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in brain, heart and skeletal muscle. Expressed at lower level in liver and lung. {ECO:0000269|PubMed:11374904}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2DAQ (NMR - ) 2NCZ (NMR - ) 2ND1 (NMR - ) 4GND (X-ray 2.27A ) 4GNE (X-ray 1.47A ) 4GNF (X-ray 1.55A ) 4GNG (X-ray 1.73A ) 4RXJ (X-ray 2.10A ) 5UPD (X-ray 1.80A ) 6CEN (X-ray 1.61A ) 6G24 (X-ray 2.10A ) 6G25 (X-ray 1.43A ) 6G27 (X-ray 1.65A ) 6G29 (X-ray 1.70A ) 6G2B (X-ray 1.61A ) 6G2C (X-ray 1.76A ) 6G2E (X-ray 1.85A ) 6G2F (X-ray 1.74A ) 6G2O (X-ray 1.81A ) 6G3P (X-ray 2.80A ) 6G3T (X-ray 2.53A ) 7CRP (EM 3.20A ) 7CRQ (EM 3.15A ) 7CRR (EM 3.48A ) 7JYN (NMR - ) |
| DBSNP | rs13034 rs2234552 |
| Subcellular location [CC] | Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. |
| Mouse PG classification | NA |
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