| Gene Information | |
|---|---|
| Gene Name | CPNE2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 548 |
| Protein Names | Copine-2 (Copine II) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000140848 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96FN4 |
| Gene Card | CPNE2 |
| Uniprot ID | Q96FN4 |
| Pfam | PF00168; PF07002 |
| In ASD | no |
| Allosteric Prediction | no (-0.776966323) |
| Ortholog in Animals | Alpaca_ CPNE2 ( ortholog_one2one ) Dog_ CPNE2 ( ortholog_one2one ) GuineaPig_ CPNE2 ( ortholog_one2one ) Macaque_ CPNE2 ( ortholog_one2one ) Mouse_ Cpne2 ( ortholog_one2one ) Pig_ CPNE2 ( ortholog_one2one ) Rat_ Cpne2 ( ortholog_one2one ) Rabbit_ CPNE2 ( ortholog_one2one ) |
| Ohnologs | CPNE7, CPNE3, CPNE6, CPNE8, CPNE9, CPNE4 |
| Paralogs | CPNE3, CPNE5, CPNE7, CPNE6, CPNE8, CPNE1, CPNE9, CPNE4 |
| Tissue | NA |
| Tissue Specificity | Expressed in the brain. Expressed in neutrophil precursors from the bone marrow and peripheral blood (PubMed:12949241). |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:P59108}. Nucleus {ECO:0000250|UniProtKB:P59108}. Cell membrane {ECO:0000250|UniProtKB:P59108}. Note=Translocates to the cell membrane and the nucleus in a calcium-dependent manner. Colocalizes with CD2 at the cell membrane. {ECO:0000250|UniProtKB:P59108}. |
| Mouse PG classification | NA |
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