Gene Information
Gene NameWFDC8
OrganismHomo sapiens (Human)
Gene Length241
Protein NamesWAP four-disulfide core domain protein 8 (Putative protease inhibitor WAP8)
Target NameNA
Target TypeNA
Gene Age886 ( ENSG00000158901 )
Evolutionary StageMammalia
AlphaFoldDBQ8IUA0
Gene CardWFDC8
Uniprot IDQ8IUA0
PfamPF00014; PF00095
In ASDno
Allosteric Predictionno (-1.287889482)
Ortholog in AnimalsAlpaca_ WFDC8 ( ortholog_one2one )
Macaque_ WFDC8 ( ortholog_one2one )
Mouse_ Wfdc8 ( ortholog_one2one )
Pig_ WFDC8 ( ortholog_one2one )
Rat_ Wfdc8 ( ortholog_one2one )
Rabbit_ WFDC8 ( ortholog_one2one )
OhnologsNA
ParalogsSPINT4, EPPIN, WFIKKN1, KIAA0319, TFPI, SPINT1, TFPI2, AMBP, SPINT2, WFIKKN2, LRP11, KIAA0319L, WFDC6
Tissueepididymis
Tissue SpecificityExpressed ubiquitously, the highest levels are found in the epididymis followed by testis and trachea.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2272955  rs2250860 
Subcellular location [CC]Secreted {ECO:0000305}.
Mouse PG classificationNA
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