| Gene Information | |
|---|---|
| Gene Name | FAAH |
| Organism | Homo sapiens (Human) |
| Gene Length | 579 |
| Protein Names | Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Fatty acid ester hydrolase) (EC 3.1.1.-) (Oleamide hydrolase 1) |
| Target Name | fatty-acid amide hydrolase 1 |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000117480 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | O00519 |
| Gene Card | FAAH |
| Uniprot ID | O00519 |
| Pfam | PF01425 |
| In ASD | no |
| Allosteric Prediction | yes (0.464016115) |
| Ortholog in Animals | Alpaca_ FAAH ( ortholog_one2one ) Dog_ FAAH ( ortholog_one2one ) GuineaPig_ FAAH ( ortholog_one2one ) Macaque_ FAAH ( ortholog_one2one ) Mouse_ Faah ( ortholog_one2one ) Pig_ FAAH ( ortholog_one2one ) Rat_ Faah ( ortholog_one2one ) Rabbit_ FAAH ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FAAH2, QRSL1 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in the brain, small intestine, pancreas, skeletal muscle and testis. Also expressed in the kidney, liver, lung, placenta and prostate. {ECO:0000269|PubMed:17015445}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs324420 rs772931153 |
| Subcellular location [CC] | Endomembrane system {ECO:0000269|PubMed:17015445}; Single-pass membrane protein {ECO:0000269|PubMed:17015445}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:17015445}. Note=Seems to be attached to intracellular membranes and a portion of the cytoskeletal network. |
| Mouse PG classification | NA |
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