| Gene Information | |
|---|---|
| Gene Name | WEE2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 567 |
| Protein Names | Wee1-like protein kinase 2 (EC 2.7.10.2) (Wee1-like protein kinase 1B) (Wee1B kinase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000214102 ) 3 ( ENSG00000263042 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P0C1S8 |
| Gene Card | WEE2 |
| Uniprot ID | P0C1S8 |
| Pfam | PF00069 |
| In ASD | yes |
| Allosteric Prediction | no (-0.358028966) |
| Ortholog in Animals | Alpaca_ WEE2 ( ortholog_one2one ) Dog_ WEE2 ( ortholog_one2one ) Macaque_ WEE2 ( ortholog_one2one ) Mouse_ Wee2 ( ortholog_one2one ) Pig_ WEE2 ( ortholog_one2one ) Rat_ Wee2 ( ortholog_one2one ) Rabbit_ WEE2 ( ortholog_one2one ) |
| Ohnologs | WEE1 |
| Paralogs | STK35, PKMYT1, EIF2AK3, EIF2AK4, EIF2AK2, WEE1, PDIK1L, EIF2AK1 |
| Tissue | NA |
| Tissue Specificity | Expressed in oocytes (at protein level) (PubMed:29606300). May also be expressed in testis (PubMed:11029659). {ECO:0000269|PubMed:11029659, ECO:0000269|PubMed:29606300}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.022222(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 5VDK (X-ray 2.70A ) |
| DBSNP | rs35672788 rs1554415096 rs200610853 rs55901099 rs35683659 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11029659, ECO:0000269|PubMed:29606300}. |
| Mouse PG classification | NA |
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