| Gene Information | |
|---|---|
| Gene Name | SATB2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 733 |
| Protein Names | DNA-binding protein SATB2 (Special AT-rich sequence-binding protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000119042 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UPW6 |
| Gene Card | SATB2 |
| Uniprot ID | Q9UPW6 |
| Pfam | PF02376; PF16557; PF00046; PF16534 |
| In ASD | no |
| Allosteric Prediction | no (-0.612838221) |
| Ortholog in Animals | Alpaca_ SATB2 ( ortholog_one2one ) Dog_ SATB2 ( ortholog_one2one ) GuineaPig_ SATB2 ( ortholog_one2one ) Macaque_ SATB2 ( ortholog_one2one ) Mouse_ Satb2 ( ortholog_one2one ) Pig_ SATB2 ( ortholog_one2one ) Rat_ Satb2 ( ortholog_one2one ) Rabbit_ SATB2 ( ortholog_one2one ) |
| Ohnologs | SATB1 |
| Paralogs | SATB1 |
| Tissue | colon, rectum |
| Tissue Specificity | High expression in adult brain, moderate expression in fetal brain, and weak expression in adult liver, kidney, and spinal cord and in select brain regions, including amygdala, corpus callosum, caudate nucleus, and hippocampus. {ECO:0000269|PubMed:14701874}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1WI3 (NMR - ) 1WIZ (NMR - ) 2CSF (NMR - ) |
| DBSNP | rs12619995 |
| Subcellular location [CC] | Nucleus matrix {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00374, ECO:0000269|PubMed:14701874}. |
| Mouse PG classification | HPG |
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