Gene Information
Gene NameSORCS3
OrganismHomo sapiens (Human)
Gene Length1222
Protein NamesVPS10 domain-containing receptor SorCS3
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000156395 )
Evolutionary StageEukaryota
AlphaFoldDBQ9UPU3
Gene CardSORCS3
Uniprot IDQ9UPU3
PfamPF00801; PF15902; PF15901
In ASDno
Allosteric Predictionno (-0.795537184)
Ortholog in AnimalsAlpaca_ SORCS3 ( ortholog_one2one )
Dog_ SORCS3 ( ortholog_one2one )
GuineaPig_ SORCS3 ( ortholog_one2one )
Macaque_ SORCS3 ( ortholog_one2one )
Mouse_ Sorcs3 ( ortholog_one2one )
Pig_ SORCS3 ( ortholog_one2one )
Rat_ Sorcs3 ( ortholog_one2one )
Rabbit_ SORCS3 ( ortholog_one2one )
OhnologsSORCS2
ParalogsSORCS1, SORCS2, SORL1, SORT1
TissueNA
Tissue SpecificityHighly expressed in brain.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Membrane;
Single-pass type I membrane protein.
Mouse PG classificationNA
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