| Gene Information | |
|---|---|
| Gene Name | SLC29A2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 456 |
| Protein Names | Equilibrative nucleoside transporter 2 (36 kDa nucleolar protein HNP36) (Delayed-early response protein 12) (Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter) (Equilibrative NBMPR-insensitive nucleoside transporter) (Hydrophobic nucleolar protein, 36 kDa) (Nucleoside transporter, ei-type) (Solute carrier family 29 member 2) |
| Target Name | equilibrative nucleoside transporter 2 |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000174669 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q14542 |
| Gene Card | SLC29A2 |
| Uniprot ID | Q14542 |
| Pfam | PF01733 |
| In ASD | no |
| Allosteric Prediction | yes (0.27511587) |
| Ortholog in Animals | Alpaca_ SLC29A2 ( ortholog_one2one ) Dog_ SLC29A2 ( ortholog_one2one ) GuineaPig_ SLC29A2 ( ortholog_one2one ) Macaque_ SLC29A2 ( ortholog_one2one ) Mouse_ Slc29a2 ( ortholog_one2one ) Pig_ SLC29A2 ( ortholog_one2one ) Rat_ Slc29a2 ( ortholog_one2one ) Rabbit_ SLC29A2 ( ortholog_one2one ) |
| Ohnologs | SLC29A1 |
| Paralogs | SLC29A1, SLC29A3, SLC29A4 |
| Tissue | NA |
| Tissue Specificity | Expressed in skeletal muscle, liver, lung, placenta, brain, heart, kidney and ovarian tissues. {ECO:0000269|PubMed:12527552, ECO:0000269|PubMed:9396714}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs8187643 rs8187644 rs8187648 |
| Subcellular location [CC] | Basolateral cell membrane {ECO:0000269|PubMed:12527552}; Multi-pass membrane protein {ECO:0000269|PubMed:12527552}. Nucleus membrane {ECO:0000269|PubMed:12527552}; Multi-pass membrane protein {ECO:0000269|PubMed:12527552}. Note=Localized at the basolateral cell membrane in polarized MDCK cells. |
| Mouse PG classification | NA |
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