| Gene Information | |
|---|---|
| Gene Name | WDR43 |
| Organism | Homo sapiens (Human) |
| Gene Length | 677 |
| Protein Names | WD repeat-containing protein 43 (U3 small nucleolar RNA-associated protein 5 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000163811 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q15061 |
| Gene Card | WDR43 |
| Uniprot ID | Q15061 |
| Pfam | PF04003; PF00400 |
| In ASD | no |
| Allosteric Prediction | no (-1.282803386) |
| Ortholog in Animals | Alpaca_ WDR43 ( ortholog_one2one ) Dog_ WDR43 ( ortholog_one2one ) GuineaPig_ WDR43 ( ortholog_one2one ) Macaque_ WDR43 ( ortholog_one2one ) Mouse_ Wdr43 ( ortholog_one2one ) Pig_ WDR43 ( ortholog_one2one ) Rat_ Wdr43 ( ortholog_one2one ) Rabbit_ WDR43 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DAW1, WDR7, COP1, TBL2, POC1B, WDR88, PAFAH1B1, WDR17, NWD1, WDR62, PAK1IP1, DCAF4L1, WDR27, WDR5B, WDR5, NEDD1, MAPKBP1, AHI1, TEP1, SNRNP40, WDR75, WDR81, POC1A, DCAF4L2, DCAF4, WDR38 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.453739(Rat);0.105057(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7MQ8 (EM 3.60A ) 7MQ9 (EM 3.87A ) 7MQA (EM 2.70A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:24219289}. Nucleus, nucleolus fibrillar center {ECO:0000269|PubMed:24219289}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q6ZQL4}. |
| Mouse PG classification | NA |
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