| Gene Information | |
|---|---|
| Gene Name | WDR36 |
| Organism | Homo sapiens (Human) |
| Gene Length | 951 |
| Protein Names | WD repeat-containing protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000134987 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8NI36 |
| Gene Card | WDR36 |
| Uniprot ID | Q8NI36 |
| Pfam | PF12894; PF04192; PF00400 |
| In ASD | no |
| Allosteric Prediction | no (-0.725319581) |
| Ortholog in Animals | Alpaca_ WDR36 ( ortholog_one2one ) Dog_ WDR36 ( ortholog_one2one ) GuineaPig_ WDR36 ( ortholog_one2one ) Macaque_ WDR36 ( ortholog_one2one ) Mouse_ Wdr36 ( ortholog_one2one ) Pig_ WDR36 ( ortholog_one2one ) Rat_ Wdr36 ( ortholog_one2one ) Rabbit_ WDR36 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PRPF19 |
| Tissue | NA |
| Tissue Specificity | Expressed in heart, placenta, liver, skeletal muscle, kidney and pancreas. In ocular tissues, strong expression in iris, sclera, ciliary muscle, ciliary body, retina and optic nerve. {ECO:0000269|PubMed:15677485}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7MQ8 (EM 3.60A ) 7MQ9 (EM 3.87A ) 7MQA (EM 2.70A ) |
| DBSNP | rs145437203 rs148041801 rs35629723 rs549211166 rs62376783 rs142088179 rs11241095 rs118204022 rs771276992 rs35703638 rs17623803 rs372059163 rs116529882 rs34595252 rs11956837 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:21051332, ECO:0000269|PubMed:22002106}. |
| Mouse PG classification | NA |
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