| Gene Information | |
|---|---|
| Gene Name | GLYR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 553 |
| Protein Names | Cytokine-like nuclear factor N-PAC (NPAC) (3-hydroxyisobutyrate dehydrogenase-like protein) (Glyoxylate reductase 1 homolog) (Nuclear protein NP60) (Nuclear protein of 60 kDa) (Nucleosome-destabilizing factor) (hNDF) (Putative oxidoreductase GLYR1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000140632 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q49A26 |
| Gene Card | GLYR1 |
| Uniprot ID | Q49A26 |
| Pfam | PF14833; PF03446; PF00855 |
| In ASD | no |
| Allosteric Prediction | no (-0.857827458) |
| Ortholog in Animals | Alpaca_ GLYR1 ( ortholog_one2one ) Dog_ GLYR1 ( ortholog_one2one ) GuineaPig_ GLYR1 ( ortholog_one2one ) Macaque_ GLYR1 ( ortholog_one2one ) Mouse_ Glyr1 ( ortholog_one2one ) Pig_ GLYR1 ( ortholog_one2one ) Rat_ Glyr1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HIBADH |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.006076(Mouse);NULL(Rat);0.041379(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2UYY (X-ray 2.50A ) 4GUR (X-ray 2.51A ) 4GUS (X-ray 2.23A ) 4GUT (X-ray 2.00A ) 4GUU (X-ray 2.30A ) 4HSU (X-ray 1.99A ) 6R1U (EM 4.36A ) 6R25 (EM 4.61A ) |
| DBSNP | rs34176249 rs2085329 rs17703111 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:16352664}. Chromosome {ECO:0000269|PubMed:29759984, ECO:0000269|PubMed:30970244}. Note=Found in actively RNAPolII-transcribed gene bodies. {ECO:0000269|PubMed:30970244, ECO:0000269|PubMed:31408337}. |
| Mouse PG classification | NA |
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