| Gene Information | |
|---|---|
| Gene Name | WDR11 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1224 |
| Protein Names | WD repeat-containing protein 11 (Bromodomain and WD repeat-containing protein 2) (WD repeat-containing protein 15) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000120008 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BZH6 |
| Gene Card | WDR11 |
| Uniprot ID | Q9BZH6 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.01996147) |
| Ortholog in Animals | Alpaca_ WDR11 ( ortholog_one2one ) Dog_ WDR11 ( ortholog_one2one ) GuineaPig_ WDR11 ( ortholog_one2one ) Macaque_ WDR11 ( ortholog_one2one ) Mouse_ Wdr11 ( ortholog_one2one ) Pig_ WDR11 ( ortholog_one2one ) Rat_ Wdr11 ( ortholog_one2one ) Rabbit_ WDR11 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs201051480 rs318240760 rs144440500 rs761599645 rs318240761 rs144531702 rs139007744 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:29263200}. Cytoplasm {ECO:0000269|PubMed:20887964}. Nucleus {ECO:0000269|PubMed:20887964, ECO:0000269|PubMed:29263200}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:29263200}. Cytoplasmic vesicle {ECO:0000269|PubMed:29426865}. Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:29426865}. Note=Shuttles from the cilium to the nucleus in response to Hh signaling (PubMed:29263200). Might be shuttling between the nucleus and the cytoplasm (PubMed:20887964). {ECO:0000269|PubMed:20887964, ECO:0000269|PubMed:29263200}. |
| Mouse PG classification | NA |
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