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Gene Information
Gene Name
WDR11
Organism
Homo sapiens (Human)
Gene Length
1821
Protein Names
PH-interacting protein (PHIP) (DDB1- and CUL4-associated factor 14) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11)
Target Name
NA
Target Type
NA
Gene Age
810 ( ENSG00000120008 )
Evolutionary Stage
Eukaryota
AlphaFoldDB
Q8WWQ0
Gene Card
PHIP
Uniprot ID
Q8WWQ0
Pfam
PF00439; PF00400
In ASD
no
Allosteric Prediction
no (-1.01996147)
Ortholog in Animals
Alpaca_ WDR11 ( ortholog_one2one )
Dog_ WDR11 ( ortholog_one2one )
GuineaPig_ WDR11 ( ortholog_one2one )
Macaque_ WDR11 ( ortholog_one2one )
Mouse_ Wdr11 ( ortholog_one2one )
Pig_ WDR11 ( ortholog_one2one )
Rat_ Wdr11 ( ortholog_one2one )
Rabbit_ WDR11 ( ortholog_one2one )
Ohnologs
NA
Paralogs
NA
Tissue
NA
Tissue Specificity
Expressed in myeloma and epidermoid carcinoma cell lines. {ECO:0000269|PubMed:11018022}.
Pharmacological Animal Models
NULL(Chimpanzee);NULL(Mouse);0.004323(Rat);0.05(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB
3MB3
(X-ray
2.25A
)
5ENB
(X-ray
1.73A
)
5ENC
(X-ray
1.59A
)
5ENE
(X-ray
1.49A
)
5ENF
(X-ray
1.37A
)
5ENH
(X-ray
1.95A
)
5ENI
(X-ray
1.69A
)
5ENJ
(X-ray
1.63A
)
5RJI
(X-ray
1.24A
)
5RJJ
(X-ray
1.15A
)
5RJK
(X-ray
1.21A
)
5RJL
(X-ray
1.31A
)
5RJM
(X-ray
1.41A
)
5RJN
(X-ray
1.44A
)
5RJO
(X-ray
1.22A
)
5RJP
(X-ray
1.24A
)
5RJQ
(X-ray
1.35A
)
5RJR
(X-ray
1.27A
)
5RJS
(X-ray
1.37A
)
5RJT
(X-ray
1.17A
)
5RJU
(X-ray
1.32A
)
5RJV
(X-ray
1.45A
)
5RJW
(X-ray
1.51A
)
5RJX
(X-ray
1.29A
)
5RJY
(X-ray
1.25A
)
5RJZ
(X-ray
1.27A
)
5RK0
(X-ray
1.24A
)
5RK1
(X-ray
1.27A
)
5RK2
(X-ray
1.24A
)
5RK3
(X-ray
1.31A
)
5RK4
(X-ray
1.28A
)
5RK5
(X-ray
1.24A
)
5RK6
(X-ray
1.24A
)
5RK7
(X-ray
1.30A
)
5RK8
(X-ray
1.27A
)
5RK9
(X-ray
1.48A
)
5RKA
(X-ray
1.33A
)
5RKB
(X-ray
1.28A
)
5RKC
(X-ray
1.24A
)
5RKD
(X-ray
1.24A
)
5RKE
(X-ray
1.29A
)
5RKF
(X-ray
1.26A
)
5RKG
(X-ray
1.28A
)
5RKH
(X-ray
1.25A
)
5RKI
(X-ray
1.27A
)
5RKJ
(X-ray
1.46A
)
5RKK
(X-ray
1.43A
)
5RKL
(X-ray
1.36A
)
5RKM
(X-ray
1.28A
)
5RKN
(X-ray
1.23A
)
5RKO
(X-ray
1.42A
)
5RKP
(X-ray
1.35A
)
5RKQ
(X-ray
1.30A
)
5RKR
(X-ray
1.37A
)
5RKS
(X-ray
1.24A
)
5RKT
(X-ray
1.24A
)
5RKU
(X-ray
1.40A
)
5RKV
(X-ray
1.28A
)
5RKW
(X-ray
1.24A
)
5RKX
(X-ray
1.24A
)
5RKY
(X-ray
1.38A
)
5S8C
(X-ray
1.25A
)
5S8D
(X-ray
1.26A
)
5S8E
(X-ray
1.24A
)
5S8F
(X-ray
1.18A
)
5S8G
(X-ray
1.19A
)
5S8H
(X-ray
1.29A
)
5S8I
(X-ray
1.30A
)
5S8J
(X-ray
1.21A
)
5S8K
(X-ray
1.24A
)
5S8L
(X-ray
1.23A
)
5S8M
(X-ray
1.20A
)
5S8N
(X-ray
1.23A
)
5S8O
(X-ray
1.67A
)
5S8P
(X-ray
1.41A
)
5S8Q
(X-ray
1.50A
)
5S8R
(X-ray
1.22A
)
5S8S
(X-ray
1.22A
)
5S8T
(X-ray
1.22A
)
5S8U
(X-ray
1.33A
)
5S8V
(X-ray
1.18A
)
5S8W
(X-ray
1.20A
)
5S8X
(X-ray
1.15A
)
5S8Y
(X-ray
1.24A
)
5S8Z
(X-ray
1.25A
)
5S90
(X-ray
1.10A
)
5S91
(X-ray
1.29A
)
5S92
(X-ray
1.19A
)
5S93
(X-ray
1.19A
)
5S94
(X-ray
1.20A
)
5S95
(X-ray
1.21A
)
5S96
(X-ray
1.17A
)
5S97
(X-ray
1.15A
)
5S98
(X-ray
1.10A
)
5S99
(X-ray
1.18A
)
5S9A
(X-ray
1.36A
)
5S9B
(X-ray
1.15A
)
5S9C
(X-ray
1.14A
)
5S9D
(X-ray
1.19A
)
5S9E
(X-ray
1.18A
)
5S9F
5S9G
(X-ray
1.09A
)
5S9H
5S9I
5S9J
(X-ray
1.15A
)
7AV8
(X-ray
1.63A
)
7AV9
(X-ray
1.23A
)
7BBO
(X-ray
1.32A
)
7BBP
(X-ray
1.99A
)
DBSNP
rs878854420
rs768324201
rs768324201
rs7747479
rs11547228
rs9350797
rs34841569
rs36048894
Subcellular location [CC]
Nucleus {ECO:0000250}.
Mouse PG classification
NA
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