| Gene Information | |
|---|---|
| Gene Name | WDFY1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 410 |
| Protein Names | WD repeat and FYVE domain-containing protein 1 (FYVE domain-containing protein localized to endosomes 1) (FENS-1) (Phosphoinositide-binding protein 1) (WD40- and FYVE domain-containing protein 1) (Zinc finger FYVE domain-containing protein 17) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000085449 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q8IWB7 |
| Gene Card | WDFY1 |
| Uniprot ID | Q8IWB7 |
| Pfam | PF01363; PF00400 |
| In ASD | no |
| Allosteric Prediction | no (-1.569063224) |
| Ortholog in Animals | Alpaca_ WDFY1 ( ortholog_one2one ) Dog_ WDFY1 ( ortholog_one2one ) GuineaPig_ WDFY1 ( ortholog_one2one ) Macaque_ WDFY1 ( ortholog_one2one ) Mouse_ Wdfy1 ( ortholog_one2one ) Pig_ WDFY1 ( ortholog_one2one ) Rat_ Wdfy1 ( ortholog_one2one ) Rabbit_ WDFY1 ( ortholog_one2one ) |
| Ohnologs | WDFY2 |
| Paralogs | WDFY2, STAM2, HGS, GGA1, TOM1, TOM1L2, GGA3, STAM, GGA2, TOM1L1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Early endosome {ECO:0000269|PubMed:11739631, ECO:0000269|PubMed:25736436}. |
| Mouse PG classification | NA |
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