| Gene Information | |
|---|---|
| Gene Name | PRSS4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 304 |
| Protein Names | Trypsin-3 (EC 3.4.21.4) (Brain trypsinogen) (Mesotrypsin) (Mesotrypsinogen) (Serine protease 3) (Serine protease 4) (Trypsin III) (Trypsin IV) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P35030 |
| Gene Card | PRSS3 |
| Uniprot ID | P35030 |
| Pfam | PF00089 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in pancreas and pancreatic fluid (at protein level) (PubMed:6698368). Expressed in pancreas and brain (PubMed:8294000). Detected in ileum (PubMed:12021776). {ECO:0000269|PubMed:12021776, ECO:0000269|PubMed:6698368, ECO:0000269|PubMed:8294000}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1H4W (X-ray 1.70A ) 2R9P (X-ray 1.40A ) 3L33 (X-ray 2.48A ) 3L3T (X-ray 2.38A ) 3P92 (X-ray 1.60A ) 3P95 (X-ray 1.30A ) 4DG4 (X-ray 1.40A ) 4U30 (X-ray 2.50A ) 4U32 (X-ray 1.65A ) 5C67 (X-ray 1.83A ) 5JBT (X-ray 1.40A ) 5TP0 (X-ray 1.25A ) 6BX8 (X-ray 1.98A ) 6GFI (X-ray 2.30A ) |
| DBSNP | rs11547028 rs855581 rs1063273 rs1048379 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:6698368}. |
| Mouse PG classification | NA |
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