| Gene Information | |
|---|---|
| Gene Name | HSST |
| Organism | Homo sapiens (Human) |
| Gene Length | 882 |
| Protein Names | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST-1) (N-heparan sulfate sulfotransferase 1) (N-HSST 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.5.1.-); Heparan sulfate N-sulfotransferase 1 (EC 2.8.2.8)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P52848 |
| Gene Card | NDST1 |
| Uniprot ID | P52848 |
| Pfam | PF12062; PF00685 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expression is most abundant in heart, liver and pancreas. {ECO:0000269|PubMed:9230113}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1NST (X-ray 2.30A ) |
| DBSNP | rs606231459 rs606231458 rs606231457 rs606231456 |
| Subcellular location [CC] | [Isoform 1]: Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:9230113}; Single-pass type II membrane protein {ECO:0000255}. Golgi apparatus, cis-Golgi network membrane {ECO:0000269|PubMed:35137078}; Single-pass type II membrane protein {ECO:0000255}.; [Isoform 3]: Golgi apparatus, cis-Golgi network membrane {ECO:0000269|PubMed:35137078}; Single-pass type II membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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