| Gene Information | |
|---|---|
| Gene Name | USP12 |
| Organism | Homo sapiens (Human) |
| Gene Length | 370 |
| Protein Names | Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.4.19.12) (Deubiquitinating enzyme 12) (Ubiquitin thioesterase 12) (Ubiquitin-hydrolyzing enzyme 1) (Ubiquitin-specific-processing protease 12) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000152484 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O75317 |
| Gene Card | USP12 |
| Uniprot ID | O75317 |
| Pfam | PF00443 |
| In ASD | yes |
| Allosteric Prediction | yes (0.124048745) |
| Ortholog in Animals | Alpaca_ USP12 ( ortholog_one2one ) Dog_ USP12 ( ortholog_one2one ) GuineaPig_ USP12 ( ortholog_one2one ) Macaque_ USP12 ( ortholog_one2one ) Mouse_ Usp12 ( ortholog_one2one ) Pig_ USP12 ( ortholog_one2one ) Rat_ Usp12 ( ortholog_one2many ) Rabbit_ USP12 ( ortholog_one2one ) |
| Ohnologs | USP46 |
| Paralogs | USP46, USP39 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.021697(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5K16 (X-ray 2.60A ) 5K1A (X-ray 2.30A ) 5K1B (X-ray 3.30A ) 5K1C (X-ray 3.00A ) 5L8W (X-ray 2.79A ) |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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