| Gene Information | |
|---|---|
| Gene Name | WBP11 |
| Organism | Homo sapiens (Human) |
| Gene Length | 641 |
| Protein Names | WW domain-binding protein 11 (WBP-11) (Npw38-binding protein) (NpwBP) (SH3 domain-binding protein SNP70) (Splicing factor that interacts with PQBP-1 and PP1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000084463 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y2W2 |
| Gene Card | WBP11 |
| Uniprot ID | Q9Y2W2 |
| Pfam | PF09429 |
| In ASD | no |
| Allosteric Prediction | no (-0.399280759) |
| Ortholog in Animals | Macaque_ WBP11 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Highly expressed in the heart, pancreas, kidney skeletal muscle, placenta and brain (at protein level). Weakly expressed in liver and lung. {ECO:0000269|PubMed:11375989}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7ABF (EM 3.90A ) 7ABG (EM 7.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus. Cytoplasm. Note=Predominantly located in the nucleus with granular heterogeneous distribution. Excluded from nucleoli in interphase cells, distributed throughout cytoplasm in dividing cells. Colocalized with SC35 and U2B in the nucleus. In the cytoplasm, associates with the intermediate filament protein vimentin. |
| Mouse PG classification | NA |
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