| Gene Information | |
|---|---|
| Gene Name | CD47 |
| Organism | Homo sapiens (Human) |
| Gene Length | 323 |
| Protein Names | Leukocyte surface antigen CD47 (Antigenic surface determinant protein OA3) (Integrin-associated protein) (IAP) (Protein MER6) (CD antigen CD47) |
| Target Name | leukocyte surface antigen cd47 |
| Target Type | Clinical trial target |
| Gene Age | 454 ( ENSG00000196776 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q08722 |
| Gene Card | CD47 |
| Uniprot ID | Q08722 |
| Pfam | PF04549; PF08204 |
| In ASD | no |
| Allosteric Prediction | no (-0.004330165) |
| Ortholog in Animals | Alpaca_ CD47 ( ortholog_one2one ) Dog_ CD47 ( ortholog_one2one ) GuineaPig_ CD47 ( ortholog_one2one ) Macaque_ CD47 ( ortholog_one2one ) Mouse_ Cd47 ( ortholog_one2one ) Pig_ CD47 ( ortholog_one2one ) Rat_ Cd47 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2JJS (X-ray 1.85A ) 2JJT (X-ray 2.30A ) 2VSC (X-ray 1.90A ) 4CMM (X-ray 1.92A ) 4KJY (X-ray 1.93A ) 5IWL (X-ray 2.80A ) 5TZ2 (X-ray 2.30A ) 5TZT (X-ray 2.89A ) 5TZU (X-ray 2.10A ) 7MYZ (X-ray 3.40A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:7691831}; Multi-pass membrane protein {ECO:0000269|PubMed:7691831}. |
| Mouse PG classification | NA |
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