| Gene Information | |
|---|---|
| Gene Name | WARS2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 360 |
| Protein Names | Tryptophan--tRNA ligase, mitochondrial (EC 6.1.1.2) ((Mt)TrpRS) (Tryptophanyl-tRNA synthetase) (TrpRS) |
| Target Name | tryptophan--trna ligase, mitochondrial |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000116874 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9UGM6 |
| Gene Card | WARS2 |
| Uniprot ID | Q9UGM6 |
| Pfam | PF00579 |
| In ASD | no |
| Allosteric Prediction | yes (0.057602975) |
| Ortholog in Animals | Alpaca_ WARS2 ( ortholog_one2one ) Dog_ WARS2 ( ortholog_one2one ) GuineaPig_ WARS2 ( ortholog_one2one ) Macaque_ WARS2 ( ortholog_one2one ) Mouse_ Wars2 ( ortholog_one2one ) Pig_ WARS2 ( ortholog_one2one ) Rat_ Wars2 ( ortholog_one2one ) Rabbit_ WARS2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | WARS1 |
| Tissue | NA |
| Tissue Specificity | Brain. {ECO:0000269|PubMed:28236339}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5EKD (X-ray 1.82A ) |
| DBSNP | rs139548132 rs1553241795 rs11552864 rs766501807 rs772867219 rs912133959 rs3790549 rs145867327 rs1170780314 rs563341344 rs17023101 |
| Subcellular location [CC] | Mitochondrion matrix {ECO:0000269|PubMed:28236339}. |
| Mouse PG classification | NA |
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