| Gene Information | |
|---|---|
| Gene Name | WARS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 471 |
| Protein Names | Tryptophan--tRNA ligase, cytoplasmic (EC 6.1.1.2) (Interferon-induced protein 53) (IFP53) (Tryptophanyl-tRNA synthetase) (TrpRS) (hWRS) [Cleaved into: T1-TrpRS; T2-TrpRS] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000140105 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | P23381 |
| Gene Card | WARS1 |
| Uniprot ID | P23381 |
| Pfam | PF00579; PF00458 |
| In ASD | no |
| Allosteric Prediction | yes (0.54047729) |
| Ortholog in Animals | Alpaca_ WARS1 ( ortholog_one2one ) Dog_ WARS1 ( ortholog_one2one ) GuineaPig_ WARS1 ( ortholog_one2one ) Macaque_ WARS1 ( ortholog_one2one ) Mouse_ Wars ( ortholog_one2one ) Pig_ WARS1 ( ortholog_one2one ) Rat_ Wars1 ( ortholog_one2one ) Rabbit_ WARS1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | WARS2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1O5T (X-ray 2.50A ) 1R6T (X-ray 2.10A ) 1R6U (X-ray 2.00A ) 1ULH (X-ray 2.31A ) 2AKE (X-ray 3.10A ) 2AZX (X-ray 2.80A ) 2DR2 (X-ray 3.00A ) 2QUH (X-ray 2.40A ) 2QUI (X-ray 2.40A ) 2QUJ (X-ray 2.42A ) 2QUK (X-ray 2.80A ) 5UJI (X-ray 2.79A ) 5UJJ (X-ray 2.10A ) |
| DBSNP | rs2234521 rs139914390 |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
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