Gene Information
Gene NameICF45
OrganismHomo sapiens (Human)
Gene Length298
Protein NamesProbable tRNA(His) guanylyltransferase (EC 2.7.7.79) (Induced in high glucose-1) (IHG-1) (Interphase cytoplasmic foci protein 45) (tRNA-histidine guanylyltransferase)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9NWX6
Gene CardTHG1L
Uniprot IDQ9NWX6
PfamPF04446; PF14413
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in many tissues. {ECO:0000269|PubMed:15459185}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3OTB  (X-ray  2.95A  3OTC  (X-ray  3.01A  3OTD  (X-ray  2.28A  3OTE  (X-ray  2.56A  7CV1  (X-ray  4.00A 
DBSNP rs201920319  rs2270812  rs1581444231 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:15459185}. Mitochondrion outer membrane {ECO:0000305|PubMed:25008184}.
Mouse PG classificationNA
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